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The Little Foundation : ウィキペディア英語版
Little Foundation

The Little Foundation is a London based charity operating internationally.
Named in honour of William Little, the English surgeon who described what became known as 'Little's disease', a spastic paralysis of both lower limbs which then became known as infantile cerebral palsy. The charity, founded in 1990 by the late Ian Dawson-Shepherd, initially focused on funding research〔"Brain project; Funded by the Little Foundation." The Times (England ) 22 Nov. 1990〕〔"Research on handicaps; Letter." The Times (England ) 30 Aug. 1991〕〔"Baby brain damage research launched." The Times (England ) 30 Jan. 1992: p.5〕 into the causes of cerebral palsy but now has broader objectives seeking to fund research into not only the causes〔Hack M., Flannery D.J., Schluchter M., Cartar L., Borawski E., Klein N.(2002) 'Outcomes in young adulthood for very-low-birth-weight infants'. N.
Engl. J. Med. 346 (3): 149-57.〕 and prevention〔Czeizel A.E.(2009) 'Periconceptional folic acid and multivitamin supplementation for the prevention of neural tube defects and other congenital abnormalities.' Birth Defects Res. A Clin. Mol. Teratol. 85 (4): 260-8.〕〔Brough L., Rees G.A., Crawford M.A., Morton R.H. and Dorman E.K.(2010) 'Effect of multiple-micronutrient supplementation on maternal nutrient status and infant birth weight and gestational age at birth in a low income, multi-ethnic population.' B. J. Nutr., 23 April: 1-9.〕 of cerebral palsy but also allied disorders which include autism, dyslexia, epilepsy, deafness and blindness, learning difficulties, and other forms of neurodevelopmental disorder.〔'The potential role for arachidonic and docosahexaenoic acids in protection against some central nervous system injuries in preterm infants' M. A. Crawford, I. Golfetto, K. Ghebremeskel, Y. Min, T. Moodley, L. Poston, A. Phylactos, S. Cunnane and W. Schmidt. Lipids 2003. Vol.38,Iss.4;p.303-315〕
On 4 November 2009, Lord Hameed, the charity's president, tabled a motion in the House of Lords asking the Government what measures have been taken to prevent cerebral palsy which now costs the NHS £4 billion every year.〔http://www.salfordonline.com/disability.php?func=viewdetails&vdetails=16449〕〔http://www.publications.parliament.uk/pa/ld200809/ldhansrd/text/91104-gc0003.htm#091104114000035〕 The total annual cost of brain disorders (covering 19 groups of disorders) has been estimated to be €798 billion for the EU alone.〔http://www.europeanbraincouncil.org/pdfs/Publications_/Cost%20of%20Disorders%20of%20the%20Brain%20in%20Europe%20-%20EurNeuro2011.pdf 'Cost of Disorders of the Brain in Europe' European Neuropsychopharmacology (2011) 21, 718–779〕
==Research==
The charity's most recent research projects include:
*Autism spectrum disorder in children with and without epilepsy
*Defining and classifying cerebral palsy
*Clinical and MRI correlates of cerebral palsy

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